This policy outlines UW-Madison specific context related to the United States Government Policy for Oversight of Dual Use Research of Concern and Pathogens with Enhanced Pandemic Potential (USG Policy for Oversight of DURC and PEPP). The policy addresses oversight and approval of life sciences research on biological agents and toxins, as well as enhancement of biological agents and toxins that have the potential to pose risks to public health, agriculture, food security, economic security, or national security.